A single cut-off value of sperm DNA fragmentation testing does not fit all

A single cut-off value of sperm DNA fragmentation testing does not fit all

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. We are delighted to read the insightful commentary by Dr. Evenson (1), a well-known pioneer in the field of SDF testing, in response to the practice recommendations on clinical utility of sperm DNA fragmentation (SDF) testing by Agarwal et al. (2). The process of protamination during spermiogenesis was discovered as e...

Sperm DNA fragmentation testing

The editors of this book, Drs. Ashok Agarwal, Ahmad Majzoub, Chak-Lam Cho and Sandro Esteves, are to be congratulated for bringing together an extensive tome on the evaluation and management of sperm DNA fragmentation. The perspectives from North America, South America, Europe, Asia and the rest of the world provide an interesting snapshot into management of the unique phenomenon of sperm DNA d...

A guide to sperm DNA fragmentation testing

Clinical usefulness of sperm DNA fragmentation testing

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. The search for the best biomarker for the diagnosis of male infertility is more evident in recent years as conventional semen analysis is not always an optimal predictor of male fertility. Since the advent of the intra-cytoplasmic sperm injection (ICSI) for male factor infertility, the pace of research related to sper...

Future direction in sperm DNA fragmentation testing

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. Dr. Rey, in his commentary (1), has provided us with a comprehensive summary of the practice recommendations proposed by Agarwal et al. (2) with additional discussion on the basic physiology of sperm DNA structure. The pros and cons of the eight available sperm DNA fragmentation (SDF) tests were listed by the author. ...